The main differences between Cartography and GIS are in their functional components:

A GIS contains these four components:

• Input 
• Database 
• Analysis 
• Output 

In contrast, a Cartographic system can be described in three components:

• Input 
• Map 
• design 
• Output 

In the present scenario, Hand Cartography is becoming an obsolete technology and is rapidly being replaced by GIS.Source